During the early stages of the COVID-19 pandemic, I co-led a global coalition of architects, engineers, health specialists, and nonprofit partners to rapidly design and operationalize a rural COVID-19 treatment center model capable of functioning in severely under-resourced communities. Building on best-practice guidance for patient flow, staff safety, infection control, supply chain, testing, waste management, and operational logistics, I coordinated with the partners a multidisciplinary design process to create a prototype that required minimal power, water, and financial resources while maintaining clinical integrity.